阿托伐他汀联合微创置管引流术与单行纯微创置管引流术治疗慢性硬.doc

阿托伐他汀联合微创置管引流术与单纯行微创置管引流术治疗慢性硬膜下血肿患者的疗效差异 官春城 郭铭 梁晓华 冯金福 余英教 （广东省粤北人民医院神经外科 韶关512000） 摘要：目的：比较阿托伐他汀联合经锥颅微创置管引流术与单纯行经锥颅微创置管引流术治疗慢性硬膜下血肿患者的临床疗效差异。方法：选取2016年1月~2018年12月我院收治的62例慢性硬膜下血肿患者作为研究对象，随机分为对照组30例和观察组32例。对照组采用经锥颅微创置管引流术治疗；观察组采用微创置管引流术联合阿托伐他汀治疗。比较两组的临床疗效、神经功能缺损评分、日常生活活动能力量表评分、并发症发生情况和疾病复发情况。结果：治疗后，观察组临床疗效明显高于对照组，差异有统计学意义，P＜0.05；观察组的神经功能缺损评分低于对照组，日常生活活动能力量表评分明显高于对照组，差异均有统计学意义，P＜0.05；观察组总并发症发生率和复发率均明显低于对照组，差异均有统计学意义，P＜0.05。结论：阿托伐他汀联合经锥颅微创置管引流术治疗慢性硬膜下血肿，可有效清除颅内血肿，改善患者神经功能，获得更好的临床疗效。 关键词：慢性硬膜下血肿；阿托伐他汀；经锥颅微创置管引流术 The Difference between Atorvastatin Combined with Minimally Invasive Catheter Drainage and Single Minimally Invasive Catheter Drainage in theTreatment of Patients with Chronic Subdural Hematoma GUAN Chun-cheng, GUO Ming, LIANG Xiao-hua, FENG Jin-fu, YU Ying-jiao (Neurosurgery Department of The Yue Bei People’s Hospital, Guangdong, Shaoguan512000) Abstract: Objective: To compare the difference between atorvastatin combined with minimally invasive catheter drainage and single minimally invasive catheter drainage in the treatment of chronic subdural hematoma patients. Methods: From January 2016 to December 2018, 62 patients with chronic subdural hematoma in our hospital were selected as research objects, and they were randomly divided into control group with 30 cases and observation group with 32 cases. The control group was treated with minimally invasive catheter drainage only, the observation group was treated with atorvastatin combined with minimally invasive catheter drainage. Compared the clinical efficacy, neurological deficit score, activity of daily living scale score, complications and disease recurrence between the two groups. Results: After the treatment, the clinical efficacy of the observation group was significantly higher than that of the control group, with statistical significance, P0.05; the neurological deficit score of the observation group was lower than that of the control group, and the activity of daily living scale score w