缝隙连接蛋白43重构在血管再狭窄中的作用.pdf

Abstract ABSTRACT effectof coronary therapeutic percutaneous Background：Thelong-dated of the incidence intervention(PCi)iscompromisedby high post-angioplasty restenosiswhichhasnotbeensolved the andfindnew yet．Toexplorepathogenesis ofRSis ahot anddifficultinresearchareaof therapy currentlysubject point cardiovascular studiesdemonstratethat pharmacology．Some gap inthe ofvascularsmoothmuscle and part process showsthatCx43 under evidence gapjunctionremodeling proliferation．Increasing conditionscan affectthefunctionofbloodvessels． many significantly pathological theroleofGJinthe of examined RS，we investigate pathogenesis Objective：To Cx43 and the betweenCx43 and expressionanalyzedrelationship expression afterballooncatheter differentin ofneointimaformation injury phasesdevelopment in will basisforthetreatmentofRS． rats，which experimental hyperlipemia provide adult ratswere into randomlyassigned Sprague-Dawley Methods：Twenty-five