原发性高血压患者血压变化与血清电解质的关系.docVIP

???? 原发性高血压患者血压变化与血清电解质的关系 ???? ????摘要　目的：研究原发性高血压(EH)患者的血压变化与血清电解质浓度之间的关系。方法：对85例EH患者和30例正常人进行动态血压、偶测血压和血清电解质检查，比较血压各参数与血清K+、Na+、Na+/K+比值之间的相关性。结果：EH患者24 h平均收缩压(SBP)、舒张压(DBP)，日间平均SBP、DBP，夜间平均SBP、DBP与血清K+浓度呈明显负相关；与Na+/K+比值呈明显正相关(均P0.01）；偶测血压与血清Na+、K+浓度和Na+/K+比值之间无相关性（P0.05）；24 h、日间、夜间平均SBP与血清Na+浓度均呈正相关（P0.01）。结论：在EH患者中，血清K+、Na+/K+比值是全日血压的决定因素之一。　　关键词　原发性高血压　动态血压　电解质 Correlations between ambulatory blood pressure and casual blood pressure with plasma electrolytes in essential hypertension LIU Xiao-jian（Department of Cardiac Function,the First Affiliated Hospital,College of Medicine,Zhejiang University,Hangzhou 310003）HU Xiao-sheng(Department of Cardiology,the First Affiliated Hospital,College of Medicine,Zhejiang University）LU Jun-sheng（Department of Cardiology,the Second Affiliated Hospital,College of Medicine, Zhejiang University） 　　Abstract　Objective:To investigate the correlations between the blood pressure and plasma electrolytes in essential hypertension(EH).Method:24 h ambulatory blood pressure (ABP), casual BP and plasma electrolyes were measured in 85 EH patients and 30 normal subjects to compare the relation between BP and plasma potassium (K),sodium (Na) and Na/K ratio.Result:24 h ABP was inversely correlated to plasma K and positive related with Na/K ratio in EH (P0.01).There were no relations between casual BP and plasma Na and K concentrations, and plasma Na/K ratio (P0.05).Positive correlation was observed between systolic BP of 24 h ABP with plasma Na(P0.01). Conclusion:The plasma K and Na/K ratio is one of the factors determining the whole day BP in EH.　　Key words　Hypertension　Ambulatory blood pressure　Electrolytes 　本研究通过监测原发性高血压(EH)患者24 h动态血压和偶测血压及血清电解质，以了解两者之间的关系，现报告如下。 1　对象与方法 1.1　对象　　85例受试者均为我院1997年9月～1998年5月门诊及住院的EH患者(EH组)，其中住院患者30例，门诊患者55例；男45例，女40例，年龄17～70(50.51±11.39)岁；EH病史1～16(平均4.5)年；其中轻度高血压〔舒张压(DBP)90～104 mmHg(1 mmHg=0.133kPa)〕48例(56.5%)，；中度高血压(DBP 105～114 mmHg)22例(25.9%)；重度高血压(DBP≥115 mmHg)15例(17.6%)。均未服用抗高血压药物或停用抗高血压药物1周，未口服或静