多廿烷醇的基础与临床 胡大一.pptVIP

多廿烷醇作用的多效性 多廿烷醇 (10Mg/d) 与普伐他汀 ( 10Mg/d) 对内皮细胞的影响 350 400 450 500 550 Policosanol Pravastatina *** ++ ** ** p0.0001; *** p0.00001, Comparison with baseline .(Wilcoxon test) ++ p0.001; Comparison between groups .( U Mann Whitney test) Casta? o, G., Má s, R., Arruzazabala, M.L. et al, 1999. Int. J. Clin. Phar. Res, XIX (4) 105-116. Cel/ml -40 -30 -20 -10 0 10 AA 1.5 Colagen ADP 1 ? 多廿烷醇 ? 阿托伐他汀 ++ p 0.001, +++ p 0.0001, +++++p0.00001Comparison between groups ( Mann Whitney U test) Castano G et al Clin Drug Inest 2003 多廿烷醇 (10 mg /d) 与阿托伐他汀 (10 mg/d) 抗