高血压合并肾损害的处理课件.ppt

Time to Primary Outcome （ ARB 与 ACEI 联合） ONTARGET Years of Follow-up C u m u l a t i v e H a z a r d R a t e s 0 . 0 0 . 0 5 0 . 1 0 0 . 1 5 0 . 2 0 0 . 2 5 0 1 2 3 4 Ramipril Tel. Ram. # at Risk Yr 1 Yr 2 Yr 3 Yr 4 R 8576 8214 7832 7473 7095 TR 8502 8134 7740 7377 7023 Tel + Ram Ram alone Reasons for Permanently Stopping Study Medications R + T N=8502 R N=8576 R + T vs. R RR P Hypotension 406 149 2.75 0.0001 Syncope 29 15 1.95 0.032 Cough 392 360 1.10 0.1885 Diarrhea 39 12 3.28 0.0001 Angioedema 18 25 0.73 0.30 Renal Impairmen