色氨酸trp操纵子.pptVIP

The trp operon P = promoter T = terminator O = operator trpR trpA P O P T T Polycistronic mRNA (encodes 5 proteins) mRNA TrpR (repressor) 5 separate proteins that were synthesized from one mRNA trpB trpC trpD trpE Attenuator TrpR Attenuation in the trp operon Effectively adds a fine tuning to the regulation of the trp operon. Several key points: 1. Transcription translation are tightly coupled in bacteria (attenuation requires this). 2. Synthesis of a leader sequence rich in Trp influences whether transcription of the trp operon is complete. 3. If [Trp] i