肿瘤学课件 胃肠道肿瘤.pptVIP

Gastro-Intestinal Tumors胃肠肿瘤 Overview 概述 Tumors of the.... 肿瘤位于 Salivary Glands 唾液腺 Esophagus 食管 Stomach 胃 Intestinal tract 肠道 Hepatobiliary System 肝胆管系统 Pancreas 胰腺 Perianal Region 肛门周围区域 Salivary Gland Tumors唾液腺肿瘤 Rare in older dogs and cats (Siamese) 老年犬和猫（暹罗猫）少见 Majority: adenocarcinomas 大多数：腺癌 Mandibular glandmost commonly affected 下颌腺常见 Biologic behavior 生物学行为: Variably locally invasive 各种局部侵犯 Metastases to regional lymph nodes common 局部淋巴结转移 Distant metastases reported 远端转移有报道 Salivary Gland Work-up 诊断 Clinical signs 临床症状: Halitosis, dysphagia, unilateral swelling 口臭,吞咽困难，单侧肿胀 Differential diagnosis 鉴别诊断: Mucoceles, abscesses, salivary gland infarction 粘液囊肿,脓肿,唾液腺梗塞, Sialoadenitis, lymphoma, reactive lymphadenopathy 涎腺炎,淋巴瘤,反应性的淋巴结病 Diagnostics:诊断 Biopsy/aspiration 活检/细针抽取细胞学检查 Regional radiographs 局部X光检查 Salivary Gland Treatment 治疗 Therapy 治疗: Aggressive surgery 手术 More conservative surgery and radiation 更多使用保守外科和放射疗法 Chemo not reported 未报道化疗 Prognosis 预后: Unknown 未知 Salivary Gland Esophageal Cancer 食道癌 0.5% of all neoplasias 不到所有肿瘤的0.5％ Histology 组织学 Squamous cell carcinoma 鳞状细胞瘤 Leiomyosarcoma 平滑肌肉瘤 Lymphoma 淋巴瘤 Fibrosarcoma 纤维肉瘤 Osteosarcoma 骨肉瘤 Sarcoma may be secondary to Spirocerca lupi 肉瘤或许会继发于卢氏尾旋线虫 Esophagus Esophageal Cancer食道癌 History病史 Weight loss, pain when swallowing, dysphagia, regurgitation, secondary aspiration pneumonia 体重减轻，吞咽疼痛，咽下困难，反胃，继发性吸入性肺炎 Work-up诊断 Radiographs, contrast esophagram, endoscopy with biopsy , fecal exam (ova spirocerca lupi ) 放射照片，对照的食管放射照片，活组织内窥镜查,粪检(卢氏尾旋线虫虫卵) Therapy治疗 Difficult because usually advanced at diagnosis 由于诊断困难治疗也滞后 Intrathoracic surgery is difficult 胸外科手术难施行 Healing problems, risk of stricture 愈合问题，存在食道狭窄的风险 RT has limited value 放疗价值有限 Prognosis预后 Poor for malignant tumors 属恶性肿瘤，预后不良 Esophagus Gastric Cancer 胃癌 1% of all malignancies 占恶性肿瘤的1％ mf 发病率雄性雌性 Dogs犬: 60-70% adenocarcinoma 60-70％腺癌 Cats 猫: - Mo