红斑狼疮疾病介绍.pptVIP

1 * 1 * 1 * Systemic lupus erythematosus: malar rash, face This is an example of a malar rash in acute systemic lupus erythematosus. #1003173 1 * 1 * 患者为年轻女性，日晒后出现的疱疹样皮损。皮肤活检示典型SLE表现。疱疹并不是SLE常见表现，可混淆诊断。 1 * 1 * #1003258 1 * 1 * 1 * 1 * 1 * Systemic lupus erythematosis: vasculitis, hands Vasculitis develops in approximately 20 percent of patients with SLE. Vasculitis may parallel lupus activity and be associated with circulating immune complexes, low levels of serum complement, and elevated levels of anti-DNA antibodies. Extensive vasculitic lesions are seen in the upper photograph. The lower photograph was taken after treatment with corticosteroids. #1003052 1 * 左侧：尺侧偏斜，掌指关节半脱位，天鹅颈畸形。弥漫性软组织肿胀。 右侧：无关节间隙狭窄或侵蚀，而在类似畸形的类风湿关节炎患者中可见狭窄和侵蚀。在SLE中见到的畸形是由于肌腱松弛引起的，而非骨破坏，可复原。这种关节病变还可见风湿热后关节炎。 1 * 1 * Vasculitis: fingers Necrotic lesions due to vasculitis are seen on the fingertips of this patient with systemic lupus erythematosus. These skin changes appeared after a rather abrupt onset of pain in the fingers, probably resulting from an occlusion of small distal arteries. Vasculitis can also produce palpable purpura, small ulcerations, and subsequent superficial depressed scars over the fingertips. #9108120 1 * Systemic lupus erythematosus: bullous lesions, palate This 14-year-old girl with systemic lupus erythematosus has diffuse erythema of the hard and soft palate associated with scattered vesicles, papules, and petechiae. A vasculitic rash is present on the tongue. No evidence of oral infection is seen. #9108070 1 * Mixed connective tissue disease: nasal septal perforation Nasal septal perforation developed in this patient with mixed connective tissue disease. A superficial mucosal ulceration may precede a septal perforation. Nonspecific in etiology, this condition can occur in systemic lupus erythematosus, Wegeners granulomatosis, syphilis, other systemic diseases, and after trauma or nasal surgery. Nasal septal perforation is often associated with recurrent epistaxis