病理学英文课件：Inflammation.pptVIP

* * * * * * * * * * * 缓激肽 * * * * * * * * * * * * * * * * Characteristics of Chronic Inflammation Long duration: months to years Persistent infection, prolonged exposure to harmful agents Prolonged tissue destruction, loss of normal structure and function Pathological features: - Lymphocytes, Macrophages, Plasma cells - fibrosis Classification of chronic inflammation Nonspecific chronic inflammation Inflammatory pseudotumor Inflammatory polyp Granulomatous inflammation Inflammatory Pseudotumor炎性假瘤 Not a real tumor Tumor-like proliferation of local tissues (parenchymal, stromal, even inflammatory cells) resulting from chronic inflammation orbit, lung, liver and spleen Inflammatory Polyp炎性息肉 Polypoid lesion of mucosa Composed of mucosal glands, inflammatory cells , and granulation tissue. nasal, cervical colorectal mucosa. Cervical polyp Granulomatous Inflammation肉芽肿性炎症 Definition: aggregates of activated macrophages. Tuberculosis Tubercle Leprosy Tuberculoid granuloma Syphilis Gumma (syphiloma) Typhoid Fever Typhoid nodule (typhoid granuloma) Sarcoidosis Noncaseating Epithelioid granuloma Crohn Disease Noncaseating Epithelioid granuloma Rheumatic fever Aschoff body Cat-scratch disease Center: Caseous necrosis peripheral: Epithelioid cells Langhans giant cells Rim: Lymphocytes Fibroblasts Tuberculous Granuloma Foreign body giant cells Classification of inflammation Clinical classification Pathological classification Etiology？ Morphology ？ Etiology 感染性 ( Infectious ) : 最常见 物理性 ( Traumatic and physical ) : 化学性 ( Chemical )：外源性、内源性 缺血 ( Ischemic )和坏死 ( Necrosis ) 异物 ( Foreign particle ) 变态反应（Allergic ) Tuberculosis Cryptococcosis Pemphigoid（类天疱疮） 毛细血管内增生性肾小球肾炎，内皮和系膜细胞弥漫性增生，上皮下驼峰状电子致密物(D)沉积 Part 4 Local and systemic manifestations of Inflammation Local signs of acute inflammation 红、肿、热、痛 edema warmth pain