糖酵解英文版.pptVIP

Glycolysis Eric Niederhoffer SIU-SOM Glucose Pyruvate Lactate 10 steps No O2 Energy (ATP) and metabolites 3 regulated steps 学习文档 Pathway Overview What does glycolysis do for us? Process Glc (Frc) monomers Form 3-C metabolites Generate ATP and NADH Input to Glycogen, PPP TCA PPP Glycogen ATP ATP NADH Glc G6P F6P F16BP DHAP + G3P 1,3-BPG 3-PG 2-PG PEP Pyr Input to TCA cycle Lactate PGK PK (reg) G3P DH LDH HK (reg) PFK-1 (reg) Regenerate NAD+ 学习文档 Regulation Glc G6P F6P F16BP DHAP + G3P 1,3-BPG 3-PG 2-PG PEP Pyr PK HK PFK-1 Epinephrine (muscle) cAMP ATP F26BP PFK-2 (active) PFK-2 (inactive) AC PK