味觉课件英文版.pptVIP

Gustation Signaling Eric Niederhoffer SIU-SOM NV B BR SR S H+ K+ Ca2+ ……… ……… ……… ……… ……… IP3 pathway cAMP pathway Na+ Ca2+ salty sour PKA P P 学习文档 Gustation (sweet) SR Ggustbg a GDP PDE AC K+ SRi RK GTP GDP cAMP ATP a GTP 5’-AMP PKA P 学习文档 * * BR: bitter receptor SR: sweet receptor IP3: inositol triphosphate NV: neurotransmitter vesicle cAMP: cyclic adenosine triphosphate PKA: protein kinase A * * Ggust: G protein GDP: guanosine diphosphate GTP: guanosine triphosphate AC: adenylate cyclase ATP: adenosine triphosphate cAMP: cyclic adenosine monophosphate PKA: protein kinase A P: phosphate RK: