蛋白质结构与功能的 关系.pptVIP

* * * * * * 胎儿 * * * * * * * * * * * * * * “MHC是种复合休,一种抗原的基因群,全称为主要组织相容性复合体,即指某一染色体上一群紧密连锁的基因群。” * * * * * T-cell activation has two important consequences. First, the activation of cytotoxic T cells results in the secretion of perforin. This 70-kd protein makes the cell membrane of the target cell permeable by polymerizing to form transmembrane pores 10 nm wide (Figure 33.31). The cytotoxic T cell then secretes proteases called granzymes into the target cell. These enzymes initiate the pathway of apoptosis (Section 18.6.6), leading to the death of the target cell and the fragmentation of its