2004～2005年我院临床常见细菌耐药性监测.docVIP

2004～2005年我院临床常见细菌耐药性监测 目录 TOC \o 1-9 \h \z \u 目录 1 正文 1 文1：2004～2005年我院临床常见细菌耐药性监测 1 1 材料和方法 3 2 结果 4 3 讨论 5 文2：2002～2005年我院临床常见细菌分离及耐药性分析 7 1 材料与方法 9 2 结果 10 3 讨论 10 参考文摘引言： 12 原创性声明（模板） 16 文章致谢（模板） 16 正文 2004～2005年我院临床常见细菌耐药性监测 文1：2004～2005年我院临床常见细菌耐药性监测 Surveillance of bacterial resistance from a hospital ABSTRACT Objective To investigate the antimicrobial resistance of clinical isolates from a hospital in Chongqing during 2004 to 2005 according to CHINET project. Methods Disc diffusion test (KB methods) was employed to study the antimicrobial resistance. WHONET5 was applied for analysis. Results In one year of study, 1380 strai were collected which were isolated fitly from each patient. , , , , coagulasenegative staphylococci, , Enterobacter cloacae and were the most common strai among isolates. The resistant rate of enterobacter to imipenem and meropenem were the lowest. The incidence of and producing ESBLs were % and %, respectively. All the ESBLs strai are susceptible to imipenem and meropenem. %, % and % of were resistant to imipenem, meropenem and ceftazidime, respectively, and pandrugresistant (PDR) strai of have exhibited in our hospital. All strai of were susceptible to imipenem and meropenem, while only % of the strai were susceptible to cefoperazoneulbactam. There are 58 strai shown the same resistant pattern among nonsusceptible strai of , and 46 of 58 isolated from the same ward. Conclusion The surveillance results in this year were similar with that in last year. There may be cloning strai of resistant to cefoperazoneulbactam in some ICU, which resulted in the resistant rate of cefoperazoneulbactam were higher than before. It is important to take measures to control the tramission of cloning strai in the hospital. KEY WORDS Bacterial resistance;Antimicrobial agents;Grampositive cocci;Gram negative bacilli 细菌耐药性的出现和传播严重影响人类的健康。细菌耐药性可导致 治疗 无效，感染加重，甚至死亡。为遏制细菌耐药性的蔓延，世界卫生组织于2000年制定了遏制细菌耐药性的全球 发展 战略。复旦大学抗生素