急性冠脉综合征冠脉病变的血管内超声研究.docVIP

急性冠脉综合征冠脉病变的血管内超声研究 目录 TOC \o 1-9 \h \z \u 目录 1 正文 1 文1：急性冠脉综合征冠脉病变的血管内超声研究 1 1 资料与方法 2 2 结果 4 3 讨论 5 文2：颈内动脉海绵窦瘘的血管内治疗 6 1 资料与方法 7 2 结果 8 3 讨论 8 参考文摘引言： 12 原创性声明（模板） 13 文章致谢（模板） 14 正文 急性冠脉综合征冠脉病变的血管内超声研究 文1：急性冠脉综合征冠脉病变的血管内超声研究 【Abstract】 Objective To investigate the characteristic of plaques through intravascular Thirthyfive patients with stable angina pectoris ( SA ) and fourtynine patients with acute coronary syndrome (ACS) (included acute myocardial infarction and utable pectoris) were examined by coronary arteriography(CAG) and intravascular ultrasound ( IVUS). We studied the culprit lesio about the characteristic of the plaque,measured the external elastic membrane crosssectional area and lumen crosssectional area,calculated the plaque area,plaque burden, eccentricity index ,and examind the remodeling index. Results Soft plaques were dominant in ACS patients （%,34/49）,and hard plaques were dominant in SA patients［% (27 /35) ,P＜］.The proportion of itability plaues,ruptured membranes,thrombosis is higher in ACS group. Also, plaque area, plaque burden and eccentricity index were all significantly larger in ACS patients than in SA patients ( all P＜ ).Positive remodeling was more frequent in ACS patients than in SA patients, whereas negative remodeling was more frequent in SA patients (P＜).Conclusion In ACS group, the incidence of plaque vulnerability and rupture,thrombosis,positive remodeling were higher than in SA group. Intravascular ultrasound is a better method to identify the quality of plaque ,which can guide the therapy. 【Key words】 coronary atherosclerosis,acute coronary syndrome,itability plaque,intravascular ultrasound 近年的研究已经表明，急性冠脉综合征（ACS）的病理基础为冠状动脉粥样硬化斑块的不稳定性［1］，如何评价斑块的不稳定性是目前研究的热点。血管内超声（IVUS）能提供管腔、管壁横截面图像, 能够分辨出斑块的大小、组成成分、分布,准确计算狭窄率，并可以观察斑块处血管的重构情况,具有冠脉造影无法比拟的优势。本研究通过IVUS检测，探讨ACS患者罪犯病变的特征，从而更好的指导临床治疗。 1 资料与方法 研究对象 选自2007年12月—2008年11月期间在胜利油田中心医院心内科84例接受冠状动脉造影（CAG）和IVUS检查的冠心病患者，入选者的诊断根据缺血性心脏病诊断标准［2］，男48例，女36例，