过敏原检测对儿童哮喘的临床意义.docVIP

过敏原检测对儿童哮喘的临床意义 目录 TOC \o 1-9 \h \z \u 目录 1 正文 1 文1：过敏原检测对儿童哮喘的临床意义 1 1资料与方法 3 文2：心肌酶谱检测对儿童手足口病的临床意义 7 1 资料与方法 7 2 结果 8 参考文摘引言： 9 原创性声明（模板） 10 文章致谢（模板） 10 正文 过敏原检测对儿童哮喘的临床意义 文1：过敏原检测对儿童哮喘的临床意义 Clinical Significance of Allergen Detection in Children with Asthma Xu Saifang, Ying Ruzhen, Zeng Qizhao Department of Asthma Outpatient, PLA 85th Hospital, Shanghai 200025, China Abstract： ObjectiveTo evaluate the clinical significance of skin prick test and serum allergen test in children with total of 120 children with asthma and 110 controls were recruited for skin prick test with dermatophagoides farinae and dermatophagoides pteronyssinus. At the same time, serum allergen test was done by immune strap mark experiment in 61 of the children with asthma. Results(1) The total positive rate of skin prick test of the 120 children with asthma was %, significantly higher than that of the controls (P). (2) The positive rate of dermatophagoides farinae was %, while the positive rate of dermatophagoides pteronyssinus was %. (3) Results of dermatophagoides farinae and dermatophagoides pteronyssinus by skin prick test were related to the grades of asthma. (4) The positive rate of serum allergen test of the 61 children with asthma was %, including reaction to dog hair (%), cat hair (%), dermatophagoides farinae (%), dermatophagoides pteronyssinus (%), and sea foods (%). (5) There was no statistically significant difference between the positive rates of skin prick test and serum allergen test. Conclusiokin prick test can be used as the fit screening test to check the allerge in children with asthma. Key words： child; asthma; skin prick test; allergen 支气管哮喘是小儿常见的呼吸系统过敏反应性疾病，是由多种因素作用而引起的多基因遗传病，发病呈现多因性和异质性。目前儿童哮喘呈上升趋势。认为环境因素较遗传因素对该病更具有危险性［1］。许多资料显示过敏原可引起气道中各种炎症细胞释放炎症介质而加剧气道炎症，从而导致气道反应性增高，诱发哮喘发作。其中吸入性过敏原是哮喘发生触发因素。因此明确过敏原对哮喘的防治有着重要的价值。目前认为皮肤点刺试验是明确哮喘诱发原因和协助诊断的简便方法。本研究是了解哮喘患者尘螨过敏情况，同时检测血清过敏原了解其他常见过敏原情况，并探讨皮肤点刺试验对儿童哮喘诊断和治疗中的临床意义。 1资料与方法 对象 哮喘组选取本院哮喘门诊2002年11月—2