医用组织黏合剂黏合兔眼巩膜穿通伤口与传统缝合的对比实验研究临床医学.docVIP

医用组织黏合剂黏合兔眼巩膜穿通伤口与传统缝合的对比实验研究临床医学 目录 TOC \o 1-9 \h \z \u 目录 1 正文 2 文1：医用组织黏合剂黏合兔眼巩膜穿通伤口与传统缝合的对比实验研究临床医学 2 1 实验动物及材料 3 2 手术分组及方法 3 3 闭合伤口手术操作时间 4 4 大体观察 4 5 眼球抗压力实验 4 6 光镜观察 4 7 电镜观察 5 8 统计学分析 5 1 手术操作时间 5 2 大体观察 5 3 巩膜伤口抗球内压力 6 4 光镜组织病 理学 观察 6 5 透射电镜检查 6 1 医用化学组织黏合剂(a氰基丙烯酸酯)原理及性质 7 2 CA黏合巩膜全层裂伤的实验分析 7 文2：玄参和附子抗鼠心肌肥厚作用的对比实验研究临床医学 8 1 材料与方法 11 2 结 果 15 3 讨 论 16 参考文摘引言： 18 原创性声明（模板） 19 文章致谢（模板） 19 正文 医用组织黏合剂黏合兔眼巩膜穿通伤口与传统缝合的对比实验研究临床医学 文1：医用组织黏合剂黏合兔眼巩膜穿通伤口与传统缝合的对比实验研究临床医学 Abstract: Objective To investigate the feasibility of adhesion of chemical tissue adhesive(2Octyl Cyanoacrylate) for sclerotic penetrating Fortyfive Japan rabbits were randomly divided into five groups,each group had nine eyes were cyanoacrylate adhesive group,left eyes were suture days 3，7，14，30 and 90 after surgery,the conditio of conjunctiva and anterior chamber were observed by Slitlamp biomicroscopy after surgery;the condition of sclerotic wound healing and cyanoacrylate adhesive degradation were observed;the teile strength of eyeball was measured;the tissue of corneal wounds were observed by light microscope and tramission electron microscope The medical adhesive quickly occluded the sclerotic penetrating wounds during surgery inflammation was not found in the eyes in the adhesive microscope observatio showed the wounds teile strengths of sclerotic wounds were increasing with ,the medical adhesive was degraded and electron microscope observatio showed that shape and structure of sclera collagen fiber and fibroblasts were similar in both The initial study demotrates the adhesion for sclerotic penetrating wound with CA is available. Key words:sclerotic;penetrating wound;tissue adhesion;cyanoacrylate;suturing;rabbits 眼球穿通伤是常见眼外伤，目前临床 治疗 方法主要是显微镜下缝线缝合。近几年，医用化学组织黏合剂因其使用便捷、安全、价廉，已被用于眼科手术治疗，但是用于治疗巩膜穿通伤的研究尚未见报道。本研究用a氰基丙烯酸正辛酯与正丁酯混合医用黏合剂黏合巩膜穿通伤口，并与医用线缝缝合方法比较，以评价化学医用黏合剂密闭巩膜穿通伤口的可行性。材料与方法 1 实验动物及材料 6月龄普通级日本大耳白兔45只，体重~(平均)，