静脉溶栓联合替罗非班治疗急性ST段抬高型心肌梗死的临床观察（预防与卫生学资料）.docVIP

静脉溶栓联合替罗非班治疗急性ST段抬高型心肌梗死的临床观察（预防与卫生学资料） 目录 TOC \o 1-9 \h \z \u 目录 1 正文 1 文1：静脉溶栓联合替罗非班治疗急性ST段抬高型心肌梗死的临床观察 1 1资料与方法 3 文2：替罗非班治疗急性ST段抬高型心肌梗死的疗效分析 7 1 资料与方法 7 2 结果 9 3 讨论 9 参考文摘引言： 10 原创性声明（模板） 11 文章致谢（模板） 11 正文 静脉溶栓联合替罗非班治疗急性ST段抬高型心肌梗死的临床观察（预防与卫生学资料） 文1：静脉溶栓联合替罗非班治疗急性ST段抬高型心肌梗死的临床观察 [Abstract]Objective To observe the efficacy and safety of intravenous thrombolysis with alteplase combined with domestic tirofiban in the treatment of ST-segment elevation acute myocardial infarction （STEAMI）.Methods 30 STEAMI patients admitted to our hospital from May 2012 to July 2013 were selected as the conventional patients met the WHO diagnostic criteria，and could receive thrombolytic therapy ≤3 hou and underwent coronary angiography （CAG） within 7 STEAMI patients admitted to our hospital from September 2013 to November 2014 were selected as the combination group，and was given thrombolysis with alteplase and tirofiban therapy from both groups were additionally given heparin injection via continuous intravenous infusion for 48 hou，ECG，myocardial enzymogram，activated partial thromboplastin time and CAG were indicato of coronary recanalization and advee drug reaction were observed，and the short-term efficacy and safety were The peak value of CK-MB，peak time of CK-MB，the resolution of ST segment ≥50% and in-hospital myocardial infarction for a second time between the combination group and the conventional group were not significant difference （P）.There were significant differences in 5-7 days infarct-related artery （IRA） blood flow TIMI grade Ⅲ and the occurrence of utable angina within seven days between the two groups （）.Conclusion Intravenous thrombolysis combined with domestic tirofiban hydrochloride in the treatment of STEAMI ≤ 3 hou is superior to the conventional thrombolysis group in improving the infarct-related artery TIMI blood flow，the non-occurrence of utable angina within 7 days，which is not increase the risk of bleeding.　[Key words]Myo