GBS培养联合阴道假丝酵母菌检测预测足月前胎膜早破的价值研究.docxVIP

GBS培养联合阴道假丝酵母菌检测预测足月前胎膜早破的价值研究 　　[摘要]目的探討b族链球菌（gbs）及外阴阴道假丝酵母菌病（vvc）联合检测用于预测未足月胎膜早破（pprom）的价值。方法选取2016年8月～2017年8月我院收住的符合入选标准的pprom孕妇227例为观察组，入院后立即行gbs培养、阴道假丝酵母菌检测;随机选取同期足月正常分娩的孕妇743例为对照组，于妊娠35～37周进行gbs培养、阴道假丝酵母菌检测;并记录两组孕妇年龄、孕周、体重指数、孕次、产次等一般资料。观察两组孕妇gbs及vvc的阳性率及两者之间的关系。结果两组孕妇的基本资料比较，差异无统计学意义（p0.05）;227例pprom孕妇中，gbs阳性率为9.69%，明显高于对照组的5.11%，且差异有统计学意义（p0.05）;观察组vvc阳性率为25.11%，明显高于对照组的18.71%，且差异有统计学意义（p0.05）;vvc阳性组孕妇gbs阳性率9.69%高于vvc阴性组5.30%，且差异有统计学意义（p0.05）。结论gbs或vvc阳性均可增加pprom发生的风险，有必要在妊娠35周前常规行gbs筛查及vvc检测来预测pprom发生的风险，并对阳性者进行治疗。 　　[关键词]b族链球菌;外阴阴道假丝酵母菌病;预测;未足月胎膜早破 　　[中图分类号]r714.433[文献标识码]b[文章编号]1673-9701（2019）10-0072-04 　　studyonthevalueofgbsculturecombinedwithcandidavaginalisdetectionforpredictingpretermprematureruptureofmembranes 　　qiuhaifanpanyuanyuanwanglianyunhuaying 　　departmentofobstetricsandgynecology，secondaffiliatedhospitalofwenzhoumedicaluniversity，wenzhou325027，china 　　[abstract]objectivetoinvestigatethevalueofcombineddetectionofgroupbstreptococcus（gbs）andvulvovaginalcandidiasis（vvc）forpredictingpretermprematureruptureofmembranes（pprom）.methodsatotalof227pregnantwomenwithppromwhowerehospitalizedfromaugust2016toaugust2017wereselectedasobservationgroup.immediatelyafteradmission，patientsweregivengbscultureanddetectionofcandidavaginalis.743casesofpregnantwomenwithtermdeliveryinthesameperiodwererandomlyselectedasthecontrolgroup，andweregivengbscultureanddetectionofcandidavaginalisat35-37thweekofpregnancy.generaldatasuchasage，gestationalweeks，bodymassindex，pregnancytime，andparityofthetwogroupswererecorded.thepositiveratesofgbsandvvcandtherelationshipbetweenthemwereobserved.resultstherewasnosignificantdifferenceinthebasicdatabetweenthetwogroups（p0.05）.amongthe227pregnantwomenwithpprom，thepositiverateofgbswas9.69%，whichwassignificantlyhigherthanthatofthecontrolgroup（5.11%），andthedifferencewasstatisticallysignificant（p0.05）.thepositiverateofvvcintheobservationgroupwas25.11%，whichwassignificantlyhigherthanthatinthecontrolgroup（18.71%），andthedif