晚期大肠癌的个体化治疗.pptxVIP

晚期大肠癌的个体化治疗;SUMMARY;Story for GI at ASCO 2008;Advances in the Treatment of Colorectal Cancer;;BOND 1: Randomized Pivotal Trial in Metastatic Colorectal Cancer;;;EPIC Study Efficacy Data;CRYSTAL: Phase III Trial of FOLFIRI +/- Cetuximab in First-line mCRC;CRYSTAL Efficacy Data;Phase III Study: Panitumumab vs Best Supportive Care;Panitumumab Improves PFS over Best Supportive Care;Only a small portion of patients responded to EGFR targeted therapiesMajority of patients suffered the side effects and high cost without benefits;EGF/EGFR Pathway;第16页/共50页;Phase III Study: Panitumumab vs Best Suppo