药理学总论全套课件.PPTXVIP

药理学总论 Pharmacology A Very Basic Intro ;What is a drug? any chemical agent which affects any biological process ;Sources of Drugs;基因工程药物过程示意图;A goal of Genomics is to find and express genes that code for unknown peptides with significant biological properties, like receptors or enzymes. In a reverse Pharmacology approach this peptide, e.g. a receptor, is then used to fish for a natural ligand . With receptor and ligand in hand the biological role of the receptor needs to be determined. Finally, screening for synthetic ligands as well as lead optimization can lead to new drug candidate