分子医学 蛋白质修饰.pptVIP

ProteinModification

蛋白质修饰

Posttranscriptionalmodificationsofinsulin2

Posttranscriptionalmodificationsincluding:RemovalofN-MetDisulfidebondformationProteolyticprocessingChemicalmodifications: Phosphorylation(磷酸化) Acetylation(乙酰化) Methylation(甲基化) Ubiquitination(泛素化) SUMOylation(smallubiquitin-relatedmodifier) Glycosylation(糖基化) Myristylation(十四烷基化)andFarnesylation(法尼基化) ……Formoreinformation,see/wiki/Posttranslational_modification3

PTM:fourcategoriesCellResearch(2014)24:143–1604

Formoreinformation,see/wiki/Posttranslational_modificationRegulationofactiv