肺癌发病机制及防治对策.pdfVIP

肺癌发病机制及防治对策

1.U2004范围

内部化是最常见的类型的内部化，也是授权的领域的内部化。

Accordigtohistologycategories,NSCLCisdivideditosquamousado-

squamouscel1carcioma,adthelatteraccoutsforalargepercetageof

totalcases.Boththeregimeaditsefficacyvarydepedigohistology

categories.Olythreecytotoxicagets,gemcitabie(GEM),pemetrexed(PEM)ad

docetaxel(DOC),arerecommededbytheNatioalComprehesiveCacer

Network(NCCN)guideliesforsecod-1iechemotherapyio-squamousNSCLC(s-

NSCLC)

Meawhile,thediseaseburdeofcacerisexpect2dtoicrease

worldwide,especiallyidevelopigcoutries

Ithepresetstudy,weaimedtocomparetheecoomicoutcomesofsecod-lie

chemotherapystrategiesforadvaceds-NSCLCfromtheperspectiveofthe

Chiesehealthcaresystem.

2.杏仁杏仁

2.1.面向中方/回配的whichrelligigwrt和

khitchratisograge“两g”.

Astate-trasitioMarkovmodelbasedothecliicalsettigiChiaad

NCCNguideliesforNSCLCwascostructedtosimulatethediseaseprogressio

ofpatietswithadvaceds-NSCLC

Ithisstudy,wefocusedodirectmedicalcostsfromtheperspectiveofthe

ChieseHealthCareSystem.Thetimehorizowassetto6years,whichreflected

theatureofdiseaseprogosis.Moretha99%ofpatietsdieditheaalysis

timeframe.Theprimaryoutcomesicludedlife-yearsgaied(LYGs),quality-

adjustedlifeyears(Q/\LYs),adcost.CostadQALYswerediscoutedat.a

aualrateof3%,iliewithChieseguideliesforpharmacogeomics

evciluatios.Icremetalcosteffectiveessrcitios(ICERs)werecalculatedasa

costperadditioalQ?\LYgaied.The3Xpercapitagrossdomestic

product(GDP)ofChiai2018($29383)wasusedasthewilligess-to-

pay(WTP)threshold,asoneofthemostoftenusedmethodtomeasurethecost-

effectivenessoftreatmentstrategi