4-Methoxycarbonylcubanecarboxylic-acid-生命科学试剂-MCE.pdfVIP

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4-Methoxycarbonylcubanecarboxylicacid

Cat.No.:HY-W058129

CASNo.:24539-28-4

分⼦式:C₁₁H₁₀O₄

分⼦量:206.2

作⽤靶点:PROTACLinkers

作⽤通路:PROTAC

储存⽅式:Storeatroomtemperature3years

*Insolvent:-80°C,6months;-20°C,1month(Storeatroom

temperature3years)

BIOLOGICALACTIVITY

⽣物活性4-Methoxycarbonylcubanecarboxylicacid是⼀种PROTAClinker，可⽤于合成PROTAC分⼦。

体外研究PROTACscontaintwodifferentligandsconnectedbyalinker;oneisaligandforanE394ubiquitinligase

andtheotherisforthetargetprotein.PROTACsexploittheintracellularubiquitin-proteasomesystemto

selectivelydegradetargetproteins.

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Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

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