BTS-67582-生命科学试剂-MCE.pdfVIP

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BTS-67582

Cat.No.:HY-19174

CASNo.:161748-40-9

分⼦式:C₁₇H₂₄N₄O₅

分⼦量:364.4

作⽤靶点:PotassiumChannel

作⽤通路:MembraneTransporter/IonChannel

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性BTS-67582是⼀种⼝服活性⾮磺酰脲类胰岛素促分泌(insulinotropic)剂和钾通道(potassiumchannel)阻滞剂

。BTS-67582影响胰岛细胞中的K+ATP通道，但其结合位点与磺酰脲类药物不同。BTS-67582是⼀种抗糖尿

病化合物。

REFERENCES

[1].SkillmanCA,RaskinP.Adouble-maskedplacebo-controlledtrialassessingeffectsofvariousdosesofBTS67,582,anovel

insulinotropicagent,onfastinghyperglycemiainNIDDMpatients.DiabetesCare.1997Apr;20(4):591-6.7,582,aNovelInsulinotropicAgent,

onFastingHyperglycemiainNIDDMPatients

[2].LouchamiK,etal.Effectof1,1-dimethyl-2-[2-morpholinophenyl]guanidinefumarateonpancreaticisletfunction.EurJPharmacol.1998

Jul10;352(2-3):289-97.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

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