Inolitazone-hydrochloride-hydrate-Efatutazone-hydrochloride-hydrate-生命科学试剂-MCE.pdfVIP

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Inolitazonehydrochloridehydrate

Cat.No.:HY-14792C

CASNo.:1048002-36-3

Synonyms:Efatutazonehydrochloridehydrate;CS-7017hydrochloride

hydrate;RS5444hydrochloridehydrate

分⼦式:C₂₇H₃₀Cl₂N₄O₅S

分⼦量:593.52

作⽤靶点:PPAR

作⽤通路:CellCycle/DNADamage;MetabolicEnzyme/Protease;Vitamin

DRelated/NuclearReceptor

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性Inolitazonehydrochloridehydrate是新型PPARγ⾼亲和性激动剂，EC50为Rosiglitazone(HY-17386)的五

⼗分之⼀，对于不表达PPARγ的RIE细胞⽆抑制性。

IC50TargetPPARγ

客户使⽤本产品发表的科研⽂献

•IntJOncol.2018Jun;52(6):1991-2000.

•FrontMicrobiol.2019Jan8:9:3257.

•ExpCellRes.2017Dec15;361(2):246-256.

•CancerMed.2018May;7(5):1955-1966.

•bioRxiv.2025Oct22.

Seemorecustomervalidationsonwww.MedChemE

REFERENCES

[1].CoplandJA,etal.Novelhigh-affinityPPARgammaagonistaloneandincombinationwithpaclitaxelinhibitshumananaplasticthyroid

carcinomatumorgrowthviap21WAF1/CIP1.Oncogene.2006Apr13;25(16):2304-17.

1/2MasterofBioactiveMolecules—您⾝边的抑制剂⼤师