m7GTP-7-Methyl-guanosine-5-triphosphate-生命科学试剂-MCE.pdfVIP

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m7GTP

Cat.No.:HY-21586A

CASNo.:26554-26-7

Synonyms:7-Methyl-guanosine-5-triphosphate

分⼦式:C₁₁H₁₈N₅O₁₄P₃

分⼦量:537.21

作⽤靶点:NucleosideAntimetabolite/Analog

作⽤通路:CellCycle/DNADamage

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性7-Methyl-guanosine-5-triphosphate(m7GTP)是⼀种鸟苷5-磷酸。7-Methyl-guanosine-5-triphosphate的

硫代磷酸酯类似物是⼀种强效的cap-dependent翻译抑制剂。

REFERENCES

[1].KowalskaJ,etal.Phosphorothioateanalogsofm7GTPareenzymaticallystableinhibitorsofcap-dependenttranslation.BioorgMed

ChemLett.2009Apr1;19(7):1921-5.

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