MELK-IN-1-Standard-生命科学试剂-MCE.pdfVIP

Hotline:400-820-3792

Inhibitors•ScreeningLibraries•Proteins

www.MedChemE

MELK-IN-1(Standard)

Cat.No.:HY-101515R

CASNo.:2095596-44-2

分⼦式:C₃₁H₃₃N₅O₄

分⼦量:539.62

作⽤靶点:MELK;ReferenceStandards

作⽤通路:PI3K/Akt/mTOR;Others

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性MELK-IN-1(Standard)是MELK-IN-1(HY-101515)的分析标准品。本产品⽤于研究及分析应⽤。MELK-IN-1是

母体胚胎亮氨酸拉链激酶(MELK)的有效抑制剂，IC50和Ki分别为3nM和0.39nM。

IC50TargetIC50:3nM(MELK)

Ki:0.39nM(MELK)

[1]

REFERENCES

[1].EdupugantiR,etal.DiscoveryofapotentinhibitorofMELKthatinhibitsexpressionoftheanti-apoptoticproteinMcl-1andTNBCcell

growth.BioorgMedChem.2017May1;25(9):2609-2616.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

Forresearchuseonly.

Tel:400-820-3792;021Fax:021E-mail:tech@MedChemE

1/1