NH2-MeO-Ph-amide-2-6-Dioxo-3-Pip-生命科学试剂-MCE.pdfVIP

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NH2-MeO-Ph-amide-(2,6-Dioxo-3-Pip)

Cat.No.:HY-W879795

CASNo.:1504209-32-8

分⼦式:C₁₃H₁₅N₃O₄

分⼦量:277.28

作⽤靶点:LigandsforE3Ligase

作⽤通路:PROTAC

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性NH2-MeO-Ph-amide-(2,6-Dioxo-3-Pip)是⼀种CRBN配体。NH2-MeO-Ph-amide-(2,6-Dioxo-3-Pip)可⽤于合

成PROTACBRD4Degrader-22(HY-155393)[1]。

IC50TargetCereblon

REFERENCES

[1].ChristianSteinebach,etal.LeveragingLigandAffinityandProperties:DiscoveryofNovelBenzamide-TypeCereblonBindersforthe

DesignofPROTACs.JMedChem.2023Oct30.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

Forresearchuseonly.

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