Nebracetam-WEB-1881-FU-生命科学试剂-MCE.pdfVIP

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Nebracetam

Cat.No.:HY-113970

CASNo.:97205-34-0

Synonyms:WEB1881FU

分⼦式:C₁₂H₁₆N₂O

分⼦量:204.27

作⽤靶点:mAChR;CalciumChannel

作⽤通路:GPCR/GProtein;NeuronalSignaling;Membrane

Transporter/IonChannel

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性Nebracetam(WEB1881FU)是⼀种⼝服有效的M1毒蕈碱受体(M1muscarinicreceptor)激动剂。

Nebracetam可引起胞内Ca2+浓度升⾼，EC50值为1.59mM。Nebracetam具有神经保护和改善认知障碍的

活性。Nebracetam可⽤于阿尔茨海默病等神经系统疾病的研究。

IC50TargetmAChR1

REFERENCES

[1].KitamuraY,etal.Effectsofnebracetam(WEB1881FU),anovelnootropic,asaM1-muscarinicagonist.JpnJPharmacol.1991

Jan;55(1):177-80.

[2].IwasakiK,etal.Effectofnebracetamonthedisruptionofspatialcognitioninrats.JpnJPharmacol.1992Feb;58(2):117-26.

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Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

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