爱爱医资源-同型半胱氨酸的检测及临床应用.pdfVIP

同型半胱氨酸的检测及

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临床应用

1

前言

Ø同型半胱氨酸（homocysteine,Hcy是一

种人体内的含硫氨基酸，为蛋氨酸和半胱氨

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酸代谢过程中的重要中间产物。

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Ø新热点:许多学者认为血液Hcy升高已成为动

脉粥样硬化发生的一个独立危险因子，也成

为基础医学和临床医学研究的新热点。

Ø新理念:伴有血浆Hcy升高(10umol/L)的原

发性高血压定义为H型高血压。2

Date2

同型半胱氨酸（Hcy能够让四分之三的高

血压患者脑卒中死亡风险增加12倍。

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3

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一、Hcy的存在形式

Ø有研究发现在正常人和高Hcy血症患者血浆

中，Hcy大部分（70％是与蛋白质结合，

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血浆中与Hcy结合的是白蛋白。

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