[妇产科与人体断面课件]19十九、卵巢肿瘤.pdfVIP

Ovarian Cancer Ovarian Cancer cancer cancer Introduction Introduction Ovarian cancer is the most common Ovarian cancer is the most common cause of death from gynecological cause of death from gynecological malignancy malignancy The fifth most common cause of cancer The fifth most common cause of cancer death after breast, lung, colon, and death after breast, lung, colon, and stomach cancer. stomach cancer. Introduction Introduction Approximately 1 woman in 70 will Approximately 1 woman in 70 will develop ovarian cancer develop ovarian cancer 1 woman in 100 will die from it. 1 woman in 100 will die from it. The overall 5-year survival rate is poor, The overall 5-year survival rate is poor, about 30%, primarily due to the late about 30%, primarily due to the late presenting nature of the disease. presenting nature of the disease. Incidence is age-related Incidence is age-related In woman less than 30 years age, the In woman less than 30 years age, the incidence is 3/100,000; incidence is 3/100,000; in ages 30-50, 21/100.000; in ages 30-50, 21/100.000; 50 years, 37/100,000; 50 years, 37/100,000; greater than 60 years, 46/100,000; greater than 60 years, 46/100,000; 75-79,54/100,000. 75-79,54/100,000. Etiology Etiology Hereditary factors Hereditary factors Site-Specific Familial Ovarian Cancer Site-Specific Familial Ovarian Cancer First-degree: mother, sister, daughter First-degree: mother, sister, daughter 7% lifetime risk 7% lifetime risk Second-degree: