一种血管支架仿真建模与支架内计算流体动力学模拟分析的新方法.docVIP

  一种血管支架仿真建模与支架内计算流体 动力学模拟分析的新方法# 吴瑕1，陈冉2* 5 10 15 （1. 浙江大学医学院附属邵逸夫医院放射科，杭州，邮编：310016； 2. 浙江大学医学院附属邵逸夫医院超声科，杭州，邮编：310016） 摘要：目的：建立一种血管支架仿真建模与支架内计算流体动力学模拟分析的新方法。方 法：应用实体建模软件 Pro/engineer wildfire3.0 建立血管内支架仿真三维模型，支架内径为 10mm，长度为 16mm，厚度为 0.5mm，由 4 个纵向长度为 4mm 的支架环组成，每个支架环 包括 6 个“V”型结构单元，两两相对形成菱形网格。将支架模型导入计算流体力学分析软 件 Ansys11.0-CFX 进行边界条件的设定后进行计算流体动力学仿真模拟分析。结果：建立 菱形网格结构支架仿真三维模型，计算流体动力学分析可见血流低流速涡流区（蓝绿色区 域）均位于支架杆侧面，低剪切力区（深蓝色区域，剪切力范围 0～0.56Pa）占整个模型表 面的比例为 8.21％。结论：应用实体建模软件 Pro/engineer wildfire3.0 和计算流体力学分析 软件 Ansys11.0-CFX 可以建立一种可行的血管支架仿真建模与支架内计算流体动力学模拟 分析的新方法。 关键词：医学影像学；支架；仿真模拟；计算流体动力学 中图分类号：R816.2 20 A Novel Method of Simulation Modeling of Stent and Intra-stent Computational Fluid Dynamics Simulation Analysis WU Xia1, CHEN Ran2 25 30 35 40 (1. Radiology department , Sir Run Run Shaw Hospital, Zhejiang University College of Medicine,Hangzhou,Post code:310016; 2. Department of Diagnostic Ultrasound and Echocardiography, Sir Run Run Shaw Hospital, Zhejiang University College of Medicine,Hangzhou,Post code:310016) Abstract: Objective: Establish a novel method of simulation modeling of stent and intra-stent computational fluid dynamics simulation analysis. Method: Stent simulation model is designed by Pro/engineer wildfire3.0,the diameter of stent is 10mm, length is 16mm,thickness is 0.5mm.The model include four stent ring which length is 4mm.Every stent ring contain six V-style unit. Fluid models are built up by importing these stent models into computational fluid dynamics software ansys11.0-CFX, then CFD analysis is proceed to study the effect of stent structure on hemodynamics. Result: Stent stimulation model with diamond style mesh is built. According to the analysis of computational fluid dynamics, the low velocity and eddy areas(blue-green area) locate in the both flanks of stent structure, the percentage of low wall shear stress on the surface of models(deep blue area, wall shear stress range from 0 to 0.56 Pa) is 8.21％. Conclusion: A feasible new method of s