甲壳素和壳聚糖化学改性研究进展.pdfVIP

第 16 卷 第 4 期 化　学　进　展 Vol. 16 No. 4 2004 年 7 月 PROGRESS IN CHEMISTRY 　July , 2004 甲壳素和壳聚糖化学改性研究进展 马　宁　汪　琴　孙胜玲　王爱勤3 ( 中国科学院兰州化学物理研究所 　兰州 730000) 摘　要 　甲壳素是一种天然多糖 ,脱除乙酰基的产物是壳聚糖 ,作为新型功能生物材料 ,它们已在水处 理、日用化学品、生物工程和医药等领域得到了应用 ,但它们不溶于一般的有机溶剂 ,从而限制了其广泛应 用。为此 , 甲壳素和壳聚糖的化学改性成为该材料研究的重要方向之一。本文综述了近年来甲壳素和壳聚 糖化学改性方面的研究进展 ,着重介绍了选择性化学修饰的方法和发展动向。 关键词 　甲壳素 　壳聚糖 　化学改性 　功能材料 ( ) 中图分类号: O636. 1 　文献标识码 : A 　文章编号 : 2004 0420643211 Progress in Chemical Modification of Chitin and Chitosan 3 Ma Ning 　Wang Qin 　Sun Shengling 　Wang Aiqin (Lanzhou Institute of Chemical Physics , Chinese Academy of Sciences , Lanzhou 730000 , China) Abstract 　Chitosan ,an amino polysaccharide obtained by deacetylation of chitin is the most abundant natural re2 sources and widely distributed in the cuticle of the Crustacea. Recently chitin and chitosan have become of great interest not only as biopolymers , but also as a new functional materials of high potential in various fields ranging from a simple floccule for waste water treatment to medical materials such as for wound healing and prevention of infection. This review has a closer look at chemical modification of chitin and chitosan. Based on current research and existing products , some new and futuristic approaches in this fascinating area are thoroughly discussed. Key words 　chitin ; chitosan ; chemical modification ; biomaterials 1) ,但它们的化学性质却有较大差别。甲壳素和壳 一、引 　言