富马酸与三种环糊精在水溶液中包合作用的研究.pdfVIP

94 2008, Vol. 29, No. 03 食品科学 ※基础研究 李彦威，石红翠，李 凤，刘 强，魏文珑，王志忠 (太原理工大学化学化工学院，山西 太原 030024) ：本实验分别探讨了α- 环糊精、β- 环糊精、羟丙基-β- 环糊精在水溶液中对富马酸的包合作用。实验采 用紫外吸收光谱法和相溶解度法研究三种环糊精在水溶液中对富马酸的包合和增溶作用，以及包合过程中热力学参 数的变化情况。结果表明，富马酸与三种环糊精在水溶液中均可自发形成了1:1(物质的量比)可溶性包合物，从而 增加了其溶解度。同时，富马酸与三种环糊精在包合过程中的吉布斯自由能变化(ΔG)、焓变(ΔH)和熵变(ΔS)均为 负值，所有过程均为焓驱动过程，且为放热过程(ΔH ＜0)和熵减过程(ΔS ＜0)。 ：富马酸；α- 环糊精；β- 环糊精；羟丙基-β- 环糊精；溶解度；热力学参数 Cyclodexteins Complexation of Fumaric Acid in Aqueous Solution LI Yan-wei，SHI Hong-cui，LI Feng，LIU Qiang，WEI Wen-long，WANG Zhi-zhong ( College of Chemistry and Chemical Engineering, Taiyuan University of Technology, Taiyuan 030024, China) Abstract ：The complexation effects of fumaric acid with α-cyclodextrin(α-CD), β-cyclodextrin(β-CD) hydroxypropyl-β- cyclodextrin(HP-β-CD) in aqueous solution were studied respectively. The intermolecular reaction between the host and guest agents, the effects of 3CDs on solubility of fumaric acid and thermodynamic parameters in the complexation were determined by the UV absorption spectra and the phase solubility. The 1:1 molar ratio of inclusion complex of fumaric acid with each CD is spontaneously formed under the experimental temperatures. All thermodynamic parameters of ΔG, ΔH and ΔS in the complexations exhibited negative values. Furthermore, the complex process is enthalpically driven and exothermic. Key words：fumaric acid；α-CD；β-CD；HP-β-CD；solubility； thermodynamic parameters 中图分类号：TQ341.1 文献标识码：A 文章编号：1002-6630(2008)03-0094-05 富马酸(fumaric acid)又称延胡索酸，常见用作食品 包合过程中有关热力学参数变化的异同点，以期为今后 和饲料添加剂。它酸味纯正而不涩，酸度约为柠檬酸 研制富马酸环糊精包合物提供理论依据。 的1.5 倍，在空气中放置不易吸潮，在食品行业可作为