淡竹叶化学成分研究.pdfVIP

ChemicalConstituentsfrom theLeavesof | l Lophatherum gracile ZHANG Jing，WANG Ying ，。ZHANGXiao—Qi，，ZHANGQing—Wen4，YEWen．Cai，， ， DepartmentofPhytochemistry,ChinaPharmaceuticalUniversity,Nanjing210009； InstituteofTraditionalChineseMedicine＆NaturalProducts．JinanUniversiyt,Guangzhou510632, GuangdongProvinceKeyLaboratoryofPharmacodynamicConstituentsofTCM andNew DrugsResearch，JinanUniversity Guangzhou510632； InstituteofChineseMedicalSciences，UniversityofMacau，China A【BSTRACT】AIM ：T0investigatethechemicalconstituentsoftheleavesofLophatherum gracile．METHoDS：Iso— lationandpurificationwerecarriedoutbyseveralcolumnchromatographicmethods．Compoundswereidentifiedbased ontheirphysicochemicalpropertiesandspectraIdata．RESULTS：Fourteencompoundswereisolatedfrom theleavesof L．gracile．ThestructureswereelucidatedassalcolinA (1a)，salcolinB (1b)，tricin(2)，luteolin(3)，afzelin(4)，tricin 7—0 一D—glucopyranoside(5)，swertiajaponin(6)，isoorientin(7)，tricin7-O—neohesperidoside(8)，vitexin(9)，isovitexin (1o)， 一(p—methoxypheny1)acrylicacid (11)， 一sitosterol(12)anddaucosterol(13)，respectively． C0NCLuSIoN： Compounds1a，lb，3—4，6—8and10—13wereisolatedfrom thisplantforthefirsttime． [KEYW0liDS】Lophatherumgracile；flavonolignan；flavonoid C【LCNumber】R284．1 D【ocumentcode】A A【rticleIDJl672—3651(2009)06—0428—04 doi：10．3724／SR J．1009．2009．00428 TheplantLophatherumgracileBrongn．(Gramineae) glucopyranoside(5)，swertiajaponin (6)，isoorientin (7)， iswidelydistributedinthesouthern China．Theleavesof tricin7-O—neohesperid0side(8)，vitexin(9)，isovitexin(10)， thisplant，alsocalledas “Dan ZhuYe”in Chinese，were 一 — methoxypheny1)acrylicacid(11)，一sitosterol(12)an