颅内肿瘤脑水肿与脑浸润程度的关系.pdfVIP

·858 · 肿瘤防治研究2009年第 36卷第 10期 DOI：1【】．3971／i．issn．1000—8578．2OO9．10．013 临床诊断 颅内肿瘤脑水肿与脑浸润程度的关系 晏 怡 ，孙晓川 ，吕发金 ，杨 刚 ，谢 兵 ，邓朝霞 ，刘 斌 CorrelativebetweenCerebralEdemaandBrainInvasionofIntracranialTumors YAN Yi ，SUN Xiao-chuan ，LV Fa—in ，YANG Gang ，XIEBing ，DENG Zhaoxia ，LIU Bin5 1．DepartmentofNeurosurgery，TheFirstA，filiatedHospitalo／Cho7tgqingMedicalUniversity， Chongqing40(){)16，China，2．Departmento／Radiology；3．Departmento／Radiolog3，Xi’?la11Hospi talofTheThirdMilitaryMedical tiversity，4．Departmento，IntensiveCareUttit；5．DepartnleTzt ofPathology，ChongqingMedicalUniversity Abstract：Objective Toanalyzetherelationshipbetweenpathologicalgradingofgliomasanddegreeof braininvasion (densityoftumorcellspresentinperitumoralarea)usingmethodsofdiffusiontensorima— ging (DTI)andpathology．Methods 1．Fifty—twohistologicallyconfirmedcasesofintracranialtumors， includingthirty gliomaswithvarying grades，twenty—twomeningiomas，wereinvolved in thisstudy． Tumorswereclassified into differentsubgroupsaccording to theestablishedpathologicalstandardsof braininvasion．2．Thevalueofedemaindex(EI)andfractionalanisotropy (FA)attheperitumoralre— gionwereanalyzedrespectivelybythevaryingMRIconventionalsequences(T1WI， W1andenhance— ment)andDTI．3．CorrelationanalysisbetweenEIandFA wasperformedamongdifferenttumorsand differentbrainaggressiveness．Results 1．TherewassignificantdifferenceofFA valuesbetween the groupsaccordingtoseverityofbraininvasion，butnosalnefindingin theothertwoparameters(EIand ADC)．Betweengliomasandmeningiomas，significantdifferencesofFA ，ADC andElwerefound．2． Therewassignificantcorrelationbetween ElandADC valuesfrom intra—‘and inter—group ofvarying tumors．However，nosuchdifferencesexistedbetweenEIandFA．Conclusion In termsoftheresu]ts ofimaginganalysis，therewasno significantly correlativebetween severity ofedema ofintracranial tumorsandtheseverityofbraininvasion