降糖药物与低血糖事件的相关性.pdfVIP

中国科技论文在线 降糖药物与低血糖事件的相关性 李亚聪，何继瑞，崔维静** （兰州大学第二医院内分泌与糖尿病临床研究中心VIP 糖尿病科，兰州 730030 ） 5 摘要：目的：调查实践中2 型糖尿病患者使用降糖药物与低血糖事件发生的相关性。方法： 回顾总结兰州大学第二医院VIP 糖尿病科 2 型糖尿病合并药物性低血糖患者的病例资料， 对150 例研究对象进行分析，收集了性别、年龄、降糖药物使用情况等数据，对收集的相关 变量先进行单因素卡方检验，再将上述因素进行多因素Logistic 回归分析。结果：单因素分 析结果显示有差异的变量是单用胰岛素、联合用药种类，多因素Logistic 回归分析结果显示 10 不同年龄组2 型糖尿病患者低血糖的发生与单用胰岛素及联合用药种类有关系。结论：不同 年龄组的2 型糖尿病患者发生药物性低血糖与单用胰岛素及降糖药物的联合用药种类相关。 关键词：2 型糖尿病；低血糖；降糖药物 中图分类号：R587.3 15 Study on the correlation of hypoglycemic agents and hypoglycema in type 2 diabetes mellitus LI Yacong, HE Jirui, CUI Weijing (Department of VIP, Lanzhou University Second Hospital, LanZhou 730030) Abstract: Objective:The aim of this study was to explore the correlation of hypoglycemic agents 20 and hypoglycema in type 2 diabetic patients. Methods:on 150 pairs of subjects which were observed in the second affiliated hospital of Lanzhou medical university. Information was including gender, age, hypoglycemic agents etc. Chi-square test was used to analyze count data on univariate analysis.Stepwise regressive multifactor analysis was performed on above factors. Results:Through univariate conditional Chi-square test ，hypoglycemia in type 2 diabetes 25 significantly Association with insulin, combined treatment (P0.05).The results of multivariate logistic analysis showed that insulin, combined treatment (P0.05)were still related to hypoglycemia in type 2 diabetes ．Conclusions:Insulin, combined treatment (P