双岐三联活菌防治婴幼儿抗生素相关性腹泻疗效分析.pdfVIP

20l1年9月第l卷第17期 双岐三联活菌防治婴幼儿抗生素相关性腹泻疗效分析 任彩云 黄家琴 安徽理工大学附属医院淮南东方医院集团总医院儿科，安徽淮南232001 【摘要 】目的探讨双岐三联活菌防治抗生素相关性腹泻的疗效。方法 将 144例呼吸道感染患儿随机分为两组，治疗组 75例，对照组69例，两组均给予抗生素治疗。治疗组同时给予双岐三联活菌口服，对两组的抗生素相关性腹泻发生情况 及疗效进行比较。结果 治疗组抗生素相关性腹泻发生率占18．67％，有效率为96．O％；对照组发生率占46．37％，有效率 为 81．2％，两组比较差异有统计学意义(P0．05o治疗组抗生素相关性腹泻的疗效明显优于对照组(PO．05o 结论 双岐三联活菌能降低抗生素相关性腹泻的发生率。对抗生素相关性腹泻的治疗有良好效果，且临床应用方便、安 全 、无任何不 良反应，值得推广应用。 【关键词 】双岐三联活菌；婴幼儿；抗生素相关性腹泻 【中图分类号】R725．6；R978．1 【文献标识码 】B 【文章编号】2095—0616(2011)17—105—02 Effi cacyofbifidtripleviablecapsulescontrolinfantsantibioticassociated diarrhea REN Caiyua HUANG Jiaqin DepartmentofPediatrics，EasternHospitalGroupAffiliatedHospitalofAnHuiUniversityofScienceandTechnolot~，Huainan232001，China [Abstract]0bjectiveToexploretheefficacyofbifidtripleviablecapsulesPreventionforAntibioticassociateddiarrheaofchildren． MethodsTotal144childrenwithRespiratoryinfectionswererandomlydividedintotwogroups，75case~inthetreatmentgroupand othersinthecontrolgroup．TheAntibiotictherapywasusedinthetwogroups，andbifidtripleviablecapsulesweregiveninthetreatment group．W ecomparetheirincidencerateandcurativeeffectofAntibioticassociateddiarrheawitheachother．ResultsTheincidencerate andeffectiverateofthetreatmentgroupwere18．67％ and96．O％ respectively．Ascontrolgroups。theincidencerateandeffectiverate were46．37％and81．2％respectively．Theincidencerateandeffectiverateofthetwogroupsshowedstatisticaldifference(P0．05)． Comparedwiththecontrolgroup。curativeeffectofthetreatmentgroupwasbetterclearly (P 0．05)．ConclusionBifidtripleviable capsulescanreducetheincidencerateofAntibioticassociateddiarrheaandhaveagoodcurativeeffectofAntibioticassociateddiarrhea． convenienceandsafetyofclinicalapplicationofBifidtripleviablecapsules，withoutanyadversereaction，shouldbewidelyapplied． [KeywordslBifidtripleviablecapsules；Infant；Antibioticassociateddiarrhea 近年来 ，大量抗生素在儿科临床的不合理应用及滥用 ，