海洋远古生物鲎体内活性物质的研究.pdfVIP

安徽农业科学袁允燥怎则灶葬造 燥枣 粤灶澡怎蚤 粤早则蚤援 杂糟蚤援 园园6 袁 34渊24冤院6512-6515 责任编辑 姜 丽 责任校对 胡剑胜 洋远古生物鲎体内活性物质的研究 1袁2 1袁2 1袁2 谢 伟 代建国 郭勇 华南理工大学 广东广州 深圳职业技术学院 广东深圳 袁 袁 1. 袁 510640 曰2. 袁 518055冤 摘要 鲎具有强的体液免疫体系和血细胞免疫体系 在鲎体内现在已经发现 多种具有生物活性的蛋白质类物质 包括一系列凝 袁 40 袁 固因子 蛋白酶抑制剂 抗菌多肽 抗菌蛋白等 笔者就鲎血淋巴中活性功能物质以及鲎天然免疫系统进行了综述 尧 尧 尧 遥 遥 关键词 鲎种属 鲎免疫因子 鲎抗菌肽 曰 曰 中图分类号 Q95-335 文献标识码 A 文章编号 0517-6611 2006冤24-6512-04 Research Advance in the Functional Substance in the Horseshoe Crab XIE Hai wei et al (Southern China Physics and Industry University, Guangzhou, Guangdong 510640) Abstract The invertebrate horseshoe crab(Tachypleus tridentatus), an anthropod, relies completely on innate immunity袁employing a unique and very efficient host defense system. The horseshoe crabs, known as living fossils, have maintained their morphology almost unchanged for the past 150 million years. Horseshoe crab is one of evolutions success stories. These living fossils have contributed immensely to biomedical research, its hemolymph contains a lot of functional substance, such as coagulation factors Factor C, B and G; Protease inhibitors; Lectins; Antimicrobial substances. In the paper those functional substances structure and their function were summarized. The study would be beneficial to the potential antimicrobial medicament and the evolution of the invertebrate animal. Key words Horseshoe crab; Functional substance; Antimicrobial peptide 1 鲎的种属及分布 状结构 最大直径可达 占血细胞总数的 以 袁 15耀20