柔肝养阴活血法对急性心肌梗死后心功能影响.DOCVIP

临床医学论文-柔肝养阴活血法对急性心肌梗死后心功能影响 ???????? 作者：李清华 陈立新 高秀强 周金杉 杨立生　李德云 【摘要】? 目的 探讨柔肝养阴活血法对急性心肌梗死（AMI）后心功能的影响。方法 将82例AMI患者随机分为2组，对照组42例予单纯西医常规治疗；治疗组40例在西医常规治疗基础上予柔肝养阴活血胶囊，每次4粒，每日3次口服，连服6个月。应用心脏超声检查2组患者AMI后(14±2)d及1个疗程后左室舒张末径（LVEDd）、左室射血分数（LVEF）、二尖瓣舒张早期血流速度峰值（E）、二尖瓣舒张晚期血流速度峰值（A），并计算E/A。结果 2组AMI后（14±2）d LVEDd、LVEF及E/A比较差异无统计学意义（P0.05）；但1个疗程后2组LVEDd、LVEF及E/A比较差异均有统计学意义（P0.01）。结论 柔肝养阴活血法可明显改善AMI后心功能。 【关键词】? 心肌梗塞；中药疗法；心脏功能试验　　 　 　Clinical research on the effect of Rouganyangyinhuoxue capsule on cardiac function after acute myocardial infarction??? 　　【Abstract】? Objective? To investigate the clinical therapeutic effect of Rouganyangyinhuoxue capsule on the dysfunction of heart after the AMI. Methods? 82 patients with AMI were divided randomly into 2 groups, with 42 in control group and 40 in treatment group. The control group was treated by routine west medicine only, while the treatment group, on the basis of control group, was treated by Rouganyangyinhuoxue capsule, 4 pills each time, 4 times a day, per os. Both groups have the same treatment course of 6 months. By cardiac ultrasonic contrast, both groups were examined before discharge and 6 months after the discharge the LVEDd, LVEF, the peak value of tachogram at prediastole (E), the peak value of tachogram at diastasis period (A) and calculated the value of E/A. Results? There was no significant difference between LVEDd, LVEF and E/A in two groups after AMI (14±2) days (P0.05). There was significant difference between LVEDd, LVEF and E/A 6 months after the discharge (P0.01). Conclusion? There is a significant therapeutic effect of Rouganyangyinhuoxue capsule on the dysfunction of heart after the AMI.??? 　　【Key words】? Myocardial infarction; TCM therapy; Tests on the cardiac function 　　急性心肌梗死（acute myocardial infarction,AMI）指心肌的急性缺血性坏死。是在冠状动脉病变的基础上，发生冠状动脉血供急剧减少或中断，使心肌严重而持久的急性缺血所致。2005-06—2007-10，我们在西医常规治疗的基础上加服柔肝养阴活血中药治疗AMI 40例，并与单纯西医常规治疗42例对照观察，现报告如下。 　　1? 资料与方法?? 　　1.1? 一般资料? 全部82例均为河北省三河市中医院中西医结合内科住院患者，均为未经溶栓治疗（发病超过6