益气养阴疏肝方对单纯肥胖儿童糖耐量低减32例干预治疗的临床观察.DOCVIP

临床医学论文-益气养阴疏肝方对单纯肥胖儿童糖耐量低减32例干预治疗的临床观察 【摘要】? 　　［目的］探讨单纯肥胖儿童糖耐量低减干预治疗有效途径。［方法］ 两组患儿均予以饮食指导，运动指导，心理指导等健康教育方案;治疗组在上述治疗的基础上给予益气养阴疏肝中药治疗。［结果］治疗组32例，29例，3例，总有效率91%；对照组30例，有效24例，无效6例，总有效率80%。两组治疗前后血糖以及糖化血红蛋白的变化比较 治疗组治疗前后空腹血糖、餐后2h血糖以及糖化血红蛋白进行比较P＜001,有显著意义。治疗组与对照组治疗后空腹血糖、餐后2h血糖以及糖化血红蛋白进行比较P＜001,有显著意义。［结论］ 益气养阴疏肝方能够改善患儿肥胖以及糖耐量低减情况。在儿童单纯性肥胖糖耐量低减的干预治疗中有良好疗效。 【关键词】? 肥胖儿童 糖耐量 益气养阴疏肝方 临床观察 　　Abstract：［Objective］ To explore effective method to pure Children Low Glucose Tolerance. ［Method］ Take health education to 2 groups of patients, i.e. diet direction, sports and mental guide; on the basis above, the treatment group was administered Chinese drugs of Yiqi Yangyin Sugan. ［Result］ For the treatment group 32 cases, 29 cases were effective, 3 had no effect, the total effective rate 91%; for the control group 30 cases, they were 24, 6, 80% respectively. Compare the blood glucose and glycosylation hemoglobin between before and after treatment of the two groups. For the treatment group, the hungry blood glucose, blood glucose 2h after diet and glycosylation hemoglobin had P＜001, with marked meaning. So was the comparison between the two groups on the indexes above, P＜001, with marked meaning. ［Conclusion］ Yiqi Yangyin Sugan Decoction can improve children fatness and low glucose tolerance, and has good curative effect in intervening treatment of children pure fat low glucose tolerance. 　　Key words: fat children; glucose tolerance; Yiqi Yangyin Sugan Decoction; clinical observation??? 　　儿童单纯性肥胖可导致糖耐量低减（IGT）及高胰岛素血症［1］。糖耐量低减是2型糖尿病（DM）发生的高危因素也是大血管疾病的重要危险因子，大部分糖耐量低减最终将转变为2型糖尿病［2］，所以对单纯性肥胖儿童糖耐量低减早期干预治疗对于Ⅱ型糖尿病的防治及临床预后至关重要。近几年来，笔者运用益气养阴疏肝方对单纯性肥胖糖耐量低减的患儿进行干预治疗，获得良好疗效，现报道如下。 　　1? 临床资料 　　11? 一般资料? 观察病例62例均为1998年至2005年我院儿科肥胖专科门诊单纯性肥胖糖耐量低减的患儿，男33例，女性29例，年龄8～15岁，随机分为治疗组32例，对照组30例，2组年龄、性别等方面无显著性差异（P＞005）具有可比性。 　　12? 诊断标准? 肥胖诊断按1985年全国九城市儿童生长发育的衡量值, 体重超过身高别体重的20%以上为肥胖，并排除其他疾病或药物所致的继发性肥胖。糖耐量低减（IGT）诊断：口服葡萄糖耐量试验（OGTT）,根据1999年WHO/ADA所定标准，糖耐量低减是指空腹血糖（FBG）＜70mmol/L而餐后2h血糖(2hPBG)在78~111mmol/L之间。