婴幼儿血管瘤治疗方法的的研究探讨。pdf.pdfVIP

华 中 科 技 大 学 硕 士 学 位 论 文 摘 要 背景：婴幼儿血管瘤是一种常见的血管性肿瘤，虽然国内外对其研究越来越深 入，但其发生发展仍无法预知，本文重在探讨治疗婴幼儿血管瘤的方法。 方法：采用手术治疗，瘤内药物注射治疗，瘤内药物注射及手术联合治疗婴幼 儿血管瘤 271 例，并评价疗效。 结果：患儿男女比为 1:1.56。81.18%的患儿在出生一个月内发病。最常发生的 部位是头面颈部（50.55% ）。手术治疗最常见的并发症是血管瘤复发 （4.43% ），瘤内药物注射常见副反应为瘤体肿胀褪色（22.14% ）。患儿 平均年龄为 8.43 月，血管瘤瘤体面积均值为 23.64cm2 。浅表型血管瘤 疗效评价最高，治愈率为 95.65% 。1 岁以内接受治疗的婴儿，对治疗的 反应优于年长的患儿。 讨论:手术、瘤内药物注射两种方法联合应用对治疗婴幼儿血管瘤疗效最佳。 根据血管瘤生长部位、类型及分期等多种因素选择综合治疗方法，提高 治疗效果及患儿家属满意度。 [关键词]婴幼儿血管瘤，治疗，手术，平阳霉素 2 华 中 科 技 大 学 硕 士 学 位 论 文 Abstract Background:The hemangioma is a common vascular tumor. Though it involutes spontaneously, results are unpredictable.We present our research of the treatment of the infantile hemangioma. Materials and methods: Atotal of 271 patients were treated during the research of 3 years. They were given operation , injections or combination of both. Response to the treatment was garded as excellent, good, or no response. Results: The male-to-female ratio was 1:1.56.In 81.18% of patients, hemangioma was noticed within first month of life. The commonest site of involvement was head and neck (50.55%).In the patients given opreations, the commonest complications was the recrudescence of hemangioma. In the patients who received the treatment of injections, the commonest clinical presentation was discoloration and swelling. Mean age and size were 8.43 months and 23.64 cm2. Pesponse rate (95.65%) was highest for superficial type using any kind of treatments. Patients younger than 1 year showed better response (90.3%) in comparison with children older than 1 year (80.8%). Conclusion: Results of the combinatio