补肾活血方治疗帕金森病的临床研究.pdfVIP

中国医药导报 2014年8月第 11卷第22期 窑中医中药 窑 补肾活血方治疗帕金森病的临床研究 陈松盛 马巧亚 王锐利 胡春婷 西安交通大学第二附属医院干部病房神经内科袁陕西西安 710004 [摘要] 目的观察补肾活血方治疗帕金森病的临床效果遥 方法 选择西安交通大学第二附属医院2006年9月耀 2012年9月门诊及住院帕金森病患者70例袁将其随机分为治疗组渊35例冤和对照组渊35例冤袁治疗组给予补肾活 血中药和西药美多巴袁对照组单用美多巴袁疗程均为3个月袁采用英国帕金森病学会脑库帕金森病临床诊断量表 渊UPDRS冤对两组患者治疗前后的症状进行评分曰同时观察两组患者的非运动症状袁包括失眠尧便秘尧多汗尧精神障 碍尧乏力尧不明原因导致的疼痛尧认知障碍等的发生率遥 结果 治疗组用药前后的UPDRS评分差较对照组大袁差 异有统计学意义渊P约0.05冤曰治疗后治疗组的非运动症状袁如失眠尧便秘尧多汗尧乏力的发生率与对照组比较袁差异 有统计学意义渊P约0.05冤曰而精神障碍尧不明原因导致的疼痛尧认知障碍等虽较对照组有所降低袁但差异无统计学 意义渊P跃0.05冤遥 结论补肾活血方可明显改善帕金森病患者的运动症状袁同时对于非运动症状如失眠尧便秘尧多 汗尧乏力等亦有明显的改善遥 [关键词] 帕金森病曰美多巴曰药物治疗曰中西医结合 [中图分类号] R742.5 [文献标识码]A [文章编号] 1673-7210渊2014冤08渊a冤-0099-04 ClinicalstudyofParkinsondiseasetreatedwithBushenHuoxueDecoction CHENSongsheng MA Qiaoya WANGRuili HU Chunting Department of Neurology, Cadre Ward, the Second Affiliated Hospital of Xian Jiaotong University, Shaanxi Province, Xian 710004, China [Abstract]ObjectiveTo observe the clinical efficacy of Bushen Huoxue Decoction on Parkinson disease. Methods 70 cases of Parkinson disease were randomly divided into treatment group (35 cases) and control group (35 cases). All the cases came from the out-patients and in-patients of the Second Affiliated Hospital of Xian Jiaotong University from September 2006 to September 2012. In treatment group, Bushen Huoxue Decoction and madopar were administered. In control group, madopar was only administered. The duration of treatment was 3 months. The unified Parkinson disease rating scale (UPDRS) was used to score the symptoms and physical signs before and after medication in two groups. The incidence of non-motor symptomsof two groupswas observed, including insomnia, profuse sweating, mental distur鄄 bance,fatigue, unk