采用DUR和DUE的方法评价寻常型银屑病患者用药情况.pdfVIP

中国药物应用与监测2011年8月第8卷第4期 Chinese Journal of Drug Application and Monitoring, Vol.8, No.4, August 2011 采用DUR和DUE 的方法评价寻常型银屑病患者用药情况 1 1 1 2 （1. 空军总医院药学部，北京 100142 ；2. 安徽医科大学临床学院药理系，安徽 合肥 230032 ） 刘　敏 ，徐　荣 ，李忠东 ，刘　杨 [摘要] 目的：建立适合本医院寻常型银屑病患者的药物利用评价程序。方法：收集和整理本医院皮肤科2008 年1月－20 10 年1 月25 例寻常型银屑病患者的相关资料，采用药物利用评价（DUR ）和药物利用评估（DUE ）方法，对患者药物利用指 数（DUI ）、评价指标、治疗药物监测及临床治疗结果进行综合分析。结果：纳入DUI 分析的药物有14 种，其中有10 种（占 7 1.43% ）药物DUI ≤1，有4 种药物DUI ＞1；DUE 结果显示：所有患者都进行了疾病严重程度评估、肝肾功能的评估、血常 规的检测。治疗药物监测指标中，肝功能和血常规监测均达到72% 。药物使用频率最高的是雷公藤多苷片，其次是维生素C 注射液。药品不良反应发生率最高的是肝功能异常。临床治疗结果指标均达到100% 。采用2 种方法评价，25 例（100% ）寻 常型银屑病患者经治疗后临床症状均得到改善，疾病得到有效缓解。结论：联合应用DUR 和DUE 方法可以更全面地评价寻 常型银屑病患者的用药情况。 [关键词] 寻常型银屑病；药物利用指数；药物利用评价；药物利用评估 [ 中图分类号] R969.3 [文献标识码] A [文章编号] 1672 – 8157(2011)04 – 0235 – 04 Evaluation of the drugs utilization of psoriasis vulgaris patients by DUR and DUE 1 1 1 2 LIU Min ，XU Rong ，LI Zhong-dong ，LIU Yang ( 1. Department of Pharmacy, General Hospital of Air Force, Beijing 100142, China; 2. Anhui Medical University, Hefei 230032, China ) [ABSTRACT] Objective: To establish the evaluation procedure of drug utilization suitable for the patients with psoriasis vulgaris in our hospital. Methods: Data of 25 psoriasis vulgaris patients in department of dermatology in our hospital from January 2008 to January 2010 were collected. DUI, evaluation index, therapeutic drug monitoring and treatment outcome were analyzed using drug utilization reliew (DUR) and drug use evaluation(DUE). Results: There were 14 kinds of drugs involved in DUI analysis. It showed that the DUIs of 10 drugs were less than 1, and that of 4 kinds of drugs were beyond 1. The outcomes of DUE showed that evaluation of disease severity, liver and kidney function evaluation and blood routine monitoring were examined in all 25 patients. The proportions