基于古籍医案的内风病证药物关联规则分析.pdfVIP

·18· Chinese Journal of Information on TCM Sep.2013 Vol.20 No.9 ·中医药信息学 · 基于古籍医案的内风病证药物关联规则分析 吴建林 山东中医药大学基础医学院,山东 济南 250355 摘要：目的 对古籍医案内风病证药物应用情况进行关联规则分析,探讨药物配伍规律及内风病证的病机特点。 方法 以《中华医典》为来源,系统收集古籍医案中记载的内风病证医案777份,对药物进行标准化处理,建立药物信 息数据库,对用药情况进行关联规则分析。结果 内风病证常用药对配伍：当归与柴胡,茯苓与柴胡,茯苓与泽泻,茯 苓与山药,当归与黄芪等；三味药常用配伍：当归、柴胡、茯苓,半夏、竹沥、生姜,茯苓、人参、陈皮,半夏、陈皮、 钩藤,当归、黄芪、人参等；四味药常用配伍：茯苓、陈皮、半夏、甘草,人参、白术、茯苓、当归,茯苓、白术、白 芍、甘草,当归、白术、白芍、甘草等；五味药常用配伍：白芍、白术、甘草、当归、茯苓,当归、白术、人参、甘 草、茯苓等。结论 关联规则分析在古籍医案中有较好的应用,可以反映病证药物配伍情况以及病机特点。 关键词：风气内动；药物；关联规则；医案 DOI：10.3969/j.issn.1005-5304.2013.09.007 中图分类号：R2-05；R255.2 文献标识码：A 文章编号：1005-5304(2013)09-0018-04 Correlation Analysis on Drugs of Endogenous Wind Syndrome Based on Collation of Ancient Medical Cases WU Jian-lin (Basic Medical College, Shandong University of TCM, Jinan 250355, China) Abstract ：Objective To analyze the association rules of drugs of endogenous wind syndrome (EWS) based on collation of ancient medical cases, and the rules of drug compatibility and pathogenesis characteristics in EWS. Methods With chief source of Chinese Medical Dictionary, 777 EWS cases were systematically collected from ancient medical documents, related drugs were standardized to establish drug information database, and the association rules of drug used were analyzed. Results The common drug pairs in EWS included Angelica and Bupleurum, Poria and Bupleurum, Poria and Alisma, Poria and Yam, Angelica and Astragalus. Three interrelated drugs were Angelica-Bupleurum-Poria, Banxia-Bamboo Lek-Ginger, Poria-Ginseng-Orange, Banxia-Orange-Hook Vine, Angelica-Astragalus-Ginseng. Four interrelated drug were Poria-Orange-Banxia-Licorice, Ginseng-Atracty