近红外光谱分析技术及其在药物分析中的应用.pptVIP

化学药品辅料库的建立 市场中常用的31种辅料 National Institutes for Food and Drug Control 欧巴代近红外导数化光谱图和滑石粉导数化光谱图 National Institutes for Food and Drug Control 药物多晶型(Polymorphisms)的鉴别 National Institutes for Food and Drug Control Absorbancein AU 三、应用NIR方法在线监测混合终点 Blend process‘ end point – homogeneous blend Beginning of the blend process National Institutes for Food and Drug Control Wavelength in nm Log(1/R) 四、药物存储稳定性的考察 0.3 0.2 0.1 0 -0.1 -0.2 -0.3 1000 1500 2000 Wavelength (nm) 2500 National Institutes for Food and Drug Control PC2(16.47%) 15 5 10