手术对OSAHS患者P-selectin及t-PA的影响.pdfVIP

—一2005北戴河国际睡眠呼吸障碍疾病大会 手术对OSAHS患者P—selectin及t-PA的影响 姚行齐1，杨长亮1，孙艺1，褚勇1，罗燕云-，王伦z (1解放军武汉总医院耳鼻喉科；2湖北省军区门诊部。湖北武汉430070) f接■】目的探讨重度阻塞性睡眠呼吸暂停低通气综合征(OsAHs)患者血栓形成机制及手术对其影响。方法 在血小板活化，凝血激活及纤溶活性下降，并与夜间低氧血症密切相关，手术可有效逆转上述改变。 【关■词l阻塞性睡眠呼吸暂停低通气综合征；血栓；手术 The of effects onP—selectinandt—pAin withobstmo． operation patients five apnea-hypopnea sleep syndrome YAO y『，CHU Lun Xingqi，YANGChangliang，SUNYong，LU0Yangyun，WANG (Department ofPLA．430070) ofotolaryngology．WuHanGeneralHoepital Toobeservethe ofsolubleP·selectinlevelsandt-PA in activity [Abstract]ObJectlve patients changes with obstructive afterthe and sleepapnea-hypopheasyndromefOSAHS)before casesofOSAHSconfirmed astheOSAHSand20normal selected bypolysomnography(PSG)weregroup donors OSAHSWOreselectedas control levelsP·selectinandt-PAWerede— without the of group．Plasma in tected．ResultsPlasmalevelsofP—selectinwas intheOSAHSthanthecontrol higher significantly group oft-PA Were as withthe intheOSAHS decreased control group(PO．05)，theactivity group compared