131例药品不良反应回顾性分析.pdfVIP

·32· ChinJPhatmacoepidemiol2008，V01．17，No．1 13 1例药品不良反应回顾性分析 崔敏①刘晓琰①曹惠明①沈金芳① 摘要目的：探讨医院药品不良反应(ADR)的发生情况及引发ADR的相关因素。方法：将医院2006年收 例。在121例化学药品所致ADR中，静脉给药引发者最多，占总例数的49．62％；抗微生物药引起的ADR居首位； 与给药途径、药品种类等多种因素相关，应加强对ADR的监测及相关知识的宣传，以减少和避免ADR的发生。 关键词药品不良反应；药品不良反应监测；合理用药 中图分类号：R95 文献标识码：A 文章编号：1005-0698(2008)0143032-03 of266 AdverseReactionCases RetrospectiveAnalysis Drug Cui Min，Liu Jinfang Xiaoyan，CaoHuiming，Shen to of affiliatedMedicalSchoolof ’DepartmentPharmacy，RenjiHospital Shanghai JiaotongUniversity，Shanghai200127，China ABSTRACT observetheoccurrenceofADRsin Objective：To a and itscorrelativefactors．Meth- hospitalanalyze od：131ADRcagescollectedina in2006were ofthe131ADRca- categorized hospital statisticallyanalyzed．Result：121 wereinducedchemical theother10 thetraditionalChinese the121ADR ．se8 by drugs，and cases，inducedby drugs．In ca- sesinduced chemical mostwereinducedintravenous 49．62％．Antimicrobial by drug，the by injection。which occupied werethefirst of tocause 77case$from42 most manifested drugs categorydrugs ADRs，totaling drugs．ADRcommonly themselvesinthe ofskinand