小剂量hCG联合HMG者卵巢刺激的疗效观察.pdfVIP

国际妇产科学杂志20 11 年10 月第38 卷第5 期 J Int Obstet Gynecol October 2011 Vol. 38 No. 5 465 论 著 小剂量hCG 联合HMG 对低促性腺激素性腺功能减退症不育患 者卵巢刺激的疗效观察 永伦 匡延平吟 要铱 目的院探讨小剂量人绒毛膜促性腺激素渊hCG 冤联合人绝经期促性腺激素渊HMG冤应用于低促性腺 激素性腺功能减退症渊HH 冤患者的卵巢刺激的可行性及其疗效遥 方法院对5 例HH 患者采用50 IU hCG 联合HMG 进行卵巢刺激 应用阴道超声尧测量血清性激素等方法监测卵泡生长发育遥 结果院4 例患者进行了诱发排卵6 个周 期 平均排卵渊2.6依1.5冤 诱发排卵成功率 100% 累积妊娠率 100% 遥 无患者改行多余卵泡穿刺术或体外受精-胚 胎移植术 未发生中尧重度卵巢过度刺激综合征 未发生高序多胎妊娠曰均分娩单胎健康婴儿遥 1 例患者进行控制 性超排卵 1 个周期 穿刺7 卵泡 获卵5 受精3 分裂形成2 优质胚胎 胚胎移植后妊娠 足月分娩 1 健康新生儿遥 结论院小剂量hCG 联合HMG 能够安全尧有效地应用于HH 患者的卵巢刺激 改善卵巢刺激的结局遥 揖关键词铱 性腺功能减退症曰 绒毛膜促性腺激素曰 不育 女渊雌冤性曰 卵泡刺激素 Effect of Ovarian Stimulation with Low -Dose hCG Combined with HMG on Infertility Patients with Hypogo nadotropic Hypogonadism FU Yong-lun K UA NG Yan-p ing. Dep artment of A ss isted Reproduction 9th Peop le 忆s Hosp ital School of Medic ine Jiaotong Univers ity Shanghai 200011 China Corresp onding author 院K UA NG Yan-p ing E-mail 院k uangyanp ing@126.com 揖Abstract Objective 院To investigate the effect of ovarian stimulation with low-dose hCG combined with HMG on infertility patients with hypogonadotropic hypogonadism. Mehtods 院Five infertility patients with hypogonadotropic hypog鄄 onadism were undergone ovarian stimulation with 50 IU hCG combined with HMG. Vaginal ultrasound -B serum sexual hormone were used to monitor determine follicular development. Results 院Four infertility patients with hypogonadotropic hypogonadism were undergone ovulation induction with six cycles the mean number of ovulation was 2.6依1.5 ovulation rate was 100% cumulating pregnancy rate was 100% . No moderate and severe OHSS occurred. No patients