川崎病患儿D_二聚体_纤维蛋白原与C_反应蛋白变化的意义_阳明玉.pdfVIP

24 19 2009 10 J App l C lin Ped ia tr, Vol. 24N o. 19, Oct. 2009 # 15 12# # # D- C- 阳明玉, 秦静庭, 杨方源, 王 昕, 张 明 (桂林医学院附属医院儿科, 广西 桂林 541001) : (KD)D-( F ib), CRP, KD , D-F ibKD( CAL) 20026- 2009 3 62 KD, CAL 16 CAL(NCAL) 46, D- F ib; D-( EL ISA), F ib, CRP30, KD SPSS 10. 0 KD D- F ib, (P 0. 05); CAL D- F ib NCAL, (P 0. 05); CAL CRPNCAL , D- F ibCRP( r= 2. 58, 2. 95 P 0. 05) D- F ibKD, CRP; D- F ib KD , , KD , 2009, 24( 19): 1512- 1513 : 皮肤黏膜淋巴结综 征; D-二聚体; C-反应蛋白; 纤维蛋白原; 冠状动脉损伤; 儿童 : R725. 4 : A : 1003- 515X( 2009) 19- 1512- 02 Changes and ClinicalSignificance of D- Dimer, Fibrinogen and C - Reaction Protein in awasakiDisease YANG M ing - yu, QIN J ing - ting, YAN G Fang - yuan, WANG X in, ZHANG M ing ( D ep rtment of P edi trics, theA ffili tedH ospit l of GuilinM edic lCollege, Guilin 541001, Gu ngx i Zhu ngA ntonom ous Region, Chin ) Abstract: Objective T o observe the ch nges of pl sm D- dmi er nd fibrinogen( F ib) level in K w s ki dise se (KD) children nd the rel tionship w ith C- re ction protein ( CRP), nd to study the v scul r injury mech nism s ofKD, nd to explore the direct rel tionship be- wt een the ch nge of pl sm D - dmi er nd F ib nd KD children who w ith coron ry rtery lesion( CAL) complic tion. Methods Sixty- two hospit lized children w ith KD from Jun. 2006 to M r. 2009 were div ided into CAL group nd non CAL ( NCAL) group b sed on the ex m in - tion results of two- dmi ension l color D oppler echoc rdiogr phy. The level of pl sm D - dmi erw sm e sured by enzyme linked mi munosor- bent ss y( EL ISA), nd F ib w sme sured by Cl uss, CRPw s investig ted by mi munoturbidmi etr ic ss y m ong 62 children w ith KD nd 30 he lthy ch ildren( he lthy control group). SPSS 10. 0 softw re w s used t